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Exposure to ultrafine particles from traffic alters the expression of many genes in human olfactory mucosa cells, a new study shows.
A new study by researchers and clinicians at UEF and Helsinki University Hospital provides novel insight into the previously unknown effects of fibroblasts in regulating blood vessel formation in vascular malformations.
The Outstanding Achievement Award is the most prestigious award conferred by the European Society of Gene and Cell Therapy, ESGCT.
Examining cortical biopsy samples from living individuals, researchers discovered early Alzheimer’s disease-associated cellular changes in three cell types.
A working-age person’s strange behaviour may be a sign of frontotemporal dementia – patient-derived cells now provide new insights into the disease. Annakaisa Haapasalo’s interest in the disease was sparked by its complex nature and strong hereditariness.
Even short-term exposure to ultra-fine particles at relatively low doses can lead to elevated cytokine levels, alter the expression of brain membrane drug transporter proteins, and affect gene expression in the olfactory bulb.
In the future, it may be possible to use microRNAs in the treatment of heart attack and ischemic stroke to help the tissue to grow new capillaries and to gain back its normal function.
Cerebrovascular disorders in the working-age population have become common in high-income countries. “In part, this is probably due to changes in lifestyles," said Docent Jukka Putaala at the XXII Nordic Stroke Society Congress in Kuopio.
The GeneT project seeks to enhance advanced manufacturing and use of gene therapy drugs in the academic environment.
Researchers at the University of Eastern Finland have identified plasma protein-based biomarkers capable of identifying adolescents at risk of developing mental health issues.