Articular cartilage can heal partially after injury – researchers found a new mechanism
For the first time, researchers have captured both biomechanical and inflammatory mechanisms in a physics-based computational model predicting cartilage degradation and a possible recovery scenario after anterior cruciate ligament injury and reconstruction.
Novel simulation-based method to assist rehabilitation planning of patients with knee osteoarthritis
MSc Amir Esrafilian’s dissertation developed different multiscale subject-specific knee joint computational modeling approaches to assess mechanical responses of knee load-bearing tissues in different functional activities such as daily activities and rehabilitation exercises.
Simple computational models can help predict patient-specific post-traumatic osteoarthritis
In MSc Paul Bolcos's thesis, a fast and reliable method of implementing patient-specific motion into computational models was developed. Using this method, patients with ACL reconstruction at risk of developing knee joint OA were identified.