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Chronically elevated blood insulin levels, or hyperinsulinemia, leads to premature senescence of human mature adipocytes and production of pro-inflammatory adipokines, according to a new study.
The Nordic POP and FinPharmaNet joint meeting was a great success, with high online turnout, top-notch speakers, and an engaged audience.
In the future, a growing number of neurodegenerative diseases could ideally be treated with the same drug, says Timo Myöhänen, the University of Eastern Finland’s newly appointed Professor of Pharmacology and Drug Development.
Nuclear receptors are transcription factors, which regulate gene expression in response to ligand binding, a feature which makes them ideal drug targets.
The doctoral thesis of Rami El-Dairi, MSc, provides novel information about placental gene expression and insights into how chemicals may disrupt normal placental physiological functions in pregnant women.
Researchers at UEF's School of Pharmacy and the Finnish Institute for Health and Welfare have received a grant of 400,000 US dollars from The Michael J. Fox Foundation.
In her PhD thesis, Krista Taipale-Kovalainen, MSc (Pharm) studied the suitability of a continuous manufacturing process with different configurations and direct-compression and dry-granulated tablet compositions.
The PhD thesis of Suchetana De, MSc, indicates the differences in ethical practices between the global commercial companies selling genetic tests online and the research setting in Finland regarding genetic testing and return of genetic test results.
Funding granted by the Research Council for Natural Sciences and Engineering to UEF researchers amounts to more than 2.1 million euros.
A rat model of early-stage Parkinson’s disease was characterised and utilised in the PhD study of Juuso Leikas, MSc (Pharm). A common anaesthetic, isoflurane, was shown to relieve Parkinson-like symptoms in the model.