Cancer Research Community Seminar Event

The current cancer research topics from University of Eastern Finland (UEF) and Kuopio University Hospital (KUH) will be presented in this seminar as posters and oral presentations. The seminar is organized by Cancer Research community.

Programme

13.30–14.00 Coffee and poster exhibition

14.00–16.45 Presentations​

Session 1. Chair Kirsi Ketola​

14.00–14.15 Einari Niskanen (UEF): Mechanisms of anti-inflammatory glucocorticoid signaling​

14.15–14.30 Enkhzaya Batnasan (UEF): Nuclear stress responses to cancer drug treatments in prostate cancer cells​

14.30–14.45 Jasmin Huttunen (UEF): Inhibition of EP300 modulates steroid receptor action in prostate cancer cells​

14.45–15.00 Marjaana Häyrinen (OU, UEF): Tumor RNA sequencing finds a poor prognosis group of MF patients. ​A close correlation with histological findings​

15.00–15.15 Emma Valima (UEF): SUMOylation inhibition potentiates glucocorticoid receptor to arrest the growth of acute lymphoblastic leukemia cells

​Break and poster exhibition

Session 2. Chair Sanna Pasonen-Seppänen​

15.45–16.00 Kaisa Mäki-Mantila (UEF): Tumor-promoting effects of M1 macrophage and cancer cell secreted extracellular vesicles in melanoma​

16.00–16.15 Heikki Kyykallio (UEF): The potential of hyaluronan-coated extracellular vesicles in cancer targeting​

16.15–16.30 Mari Lahnalampi (UEF): Characterization of leukemias at single cell level

16.30–16.45 Antti Turunen (KUH): Autograft cellular composition and outcome in hematological patients​

16.45–17.00 Closing words​

Poster exhibition

Mari Lahnalampi (UEF): Dynamic evolution of TCF3-PBX1 leukemias at single-cell level under chemotherapy pressure​

Konstantin Ivanov (UEF): Deep variational autoencoder modelling of multimodal single-cell data resolves molecular fingerprints of pre-leukemic states​

Sanni Moisio (UEF): Genomic determinants of therapy response in ETV6-RUNX1 leukemia​

Raju Gudhe (UEF): Breast cancer subtype classification using interpretable nuclei features derived from pathology slides​

Minna Harmanen (UEF): Improved survival in patients with mantle cell lymphoma between 2000 to 2020 during the rituximab era​​

Kirsi Kainulainen (UEF): M1 macrophages induce pro-tumor inflammation in melanoma cells via TNFR–NF-κB signaling​

Roosa Kaarijärvi (UEF): DPYSL5 Promotes Cellular Stemness and Transdifferentiation and is Highly Expressed intreatment-induced Neuroendocrine Prostate Cancer​

Heidi Kaljunen (UEF): Fanci is a master regulator of Fanconi anemia pathway in prostate cancer​

Tea Metsävainio (UEF, KUH): Gynecological cancer and family-centered care​

Tommi Patinen (UEF): Dissecting the protein interactome of wild type and lung cancer associated gain-of-function mutants of NRF2​

Mauro Scaravilli (UEF): RNA-binding protein FUS/TLS regulates oncogenic gene fusion products in prostate cancer

Jouni Kujala (UEF): Circulating cell-free DNA reflects the evolution of metastatic breast cancer

For further information, please contact Maarit Sillanpää, maarit.sillanpaa@uef.fi