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Cancer Drug Discovery

  • Summer school
  • Webinar
  • Health and well-being
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The Cancer Drug Discovery Summer School 1.-3.6.2021 is organized online by Cancer Research Community at the University of Eastern Finland.  Lectures are free of charge and open to all interested. Please register by 15.5.2021. 

Course description: 
This course will present state-of-the-art science in cancer drug discovery. The course consists of three days of seminars including attendee presentations on the day 3. The goal of the course is to gain a wide overview of cancer drug discovery introduced by top-level cancer researchers nationally and internationally. 
The course includes a range of aspects from molecular target discovery, structural and chemical biology, use of tissue organoids and in vivo models for drug discovery. The course will consist of latest techniques, analysis methods and bioinformatics related to cellular, tissue, high throughput, sequencing and imaging technologies utilized in different stages or drug discovery process. The methods are presented in the contexts of real-life research questions and projects, providing attendees with knowledge of the state-of-the-art science performed both in UEF and the represented institutes. Not only will this course be useful to researchers working in cancer research, but the techniques are applicable to other research fields as well.  

Credit points: 1–2

  • 1 for attendance at lectures both days
  • 2 for attendance at the lectures both days and a presentation on day 3. 

Course directors: Kirsi Ketola, Anna-Liisa Levonen, Leena Latonen, Sanna Pasonen-Seppänen 
Organizing Units: RC Cancer, Institute of Biomedicine & A.I. Virtanen Institute for Molecular Sciences at the University of Eastern Finland 
For more information, please contact course directors: Kirsi Ketola, email; Anna-Liisa Levonen, email; Leena Latonen, email; Sanna Pasonen-Seppänen, email  
Course secretary: Maarit Sillanpää, email  

Day 1 - Tuesday,  1 June  
Opening of the course 
08.30-09.00  Connections 
09.00-09.10  Opening words, Kirsi Ketola 
Session 1: Target Discovery in Cancer 
Session chair: Kirsi Ketola  
09.10-09.40 Keynote: Mads Daugaard, University of British Columbia, Vancouver and VAR2 Pharmaceuticals and OncoMal, Canada: 
Novel tumour targeting systems based on parasite-derived recombinant proteins  
09.40-10.10  Kari Kurppa, University of Turku: TBA 
10.10-10.40  Juha Rantala, Misvik Biology Oy, Turku:  Predictive ex vivo therapy efficacy modelling in rare cancers  
10.40-11.10  Emmy Verschuren, Institute for Molecular Medicine Finland, UH: TBA 
11.10-12.00  Lunch break
Session 2: Proteomics-based target identification 
Session chair: Mauro Scaravilli   
12.00-12.30  Markku Varjosalo, University of Helsinki: TBA 
12.30-13.00  Tetsuya Terasaki, University of Eastern Finland: TBA 
13.00-13.30  Leena Latonen, University of Eastern Finland: Integrative proteogenomics of prostate cancer
13.30-14.00  Jorma Palvimo, University of Eastern Finland: Steroid receptor protein interactomes 
14.00-14.20 Coffee break 
Session 3: Methodologies and drug discovery  
Session chair: Anna-Liisa Levonen 
14.20-14.50 Taru Muranen, Harvard Medical School, Boston, USA: The role of tumor microenvironment on drug resistance 
14.50-15.20 Nada Lallous, Vancouver Prostate Centre, University of British Columbia, Canada: Protein bioengineering for Target Discovery   
15.20-15.50 Meet the expert session in Zoom groups 
Day 2 - Wednesday, 2 June 

Session 4: Precision medicine and Industrial collaboration 
Chair: Leena Latonen 
9.00-9.30 Vittorio Fortino, Biomedicine, University of Eastern Finland: TBA 
9.30-10.00 Anu Moilanen, Orion Pharma: TBA 
10.00-10.30 TBA 
10.30-10.50 Coffee break 
Session 5: Structural Biology and Pharmacology  
Chair: Heidi Kaljunen 
10.50-11.20 Minna Rahnasto-Rilla, School of Pharmacy, University of Eastern Finland: Dual role of SIRT6 in cancer  
11.20-11.50 Antti Poso, School of Pharmacy, University of Eastern Finland: Molecular modelling and anti-cancer drug design  
11.50-12.20 Kristiina Huttunen, University of Eastern Finland: Targeted drugs for improved treatment of brain tumors  
12.20-13.00 Lunch 
Session 6: Cancer Immunotherapies 
Chair: Sanna Pasonen-Seppänen 
13.00-13.30 Diana Schenkwein, A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland: CAR-T therapies in cancer  
13.30-14.00 Tuija Kekäräinen, Kuopio Center for Gene and Cell Therapy: Cellular immunotherapies; developing future therapies for cancer 
14-14.15 Coffee break
14.15-14.45 Satu Mustjoki, University of Helsinki: TBA 
14.45-15.15 Sirpa Jalkanen, University of Turku: TBA 
15.15-15.45 Meet the expert session in Zoom groups 
Closing remarks: Leena Latonen 
 Day 3 - Thursday, 3 June 
Selected 15 min presentations at 9-16.