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Teenagers walking on city street.

Natural drop in insulin resistance in mid-adolescence protects against worsening arterial stiffness if sustained

Significant physiologic decrease in insulin resistance during mid-adolescence may stop and reverse arterial stiffness progression, a paper published in the American Journal of Physiology-Endocrinology and Metabolism concludes. The study was conducted in collaboration between Baylor College of Medicine in the United States, Texas Children’s Hospital Heart Center in the United States, the University of Abuja in Nigeria, Guista Health Foundation in Nigeria, the University of Bristol in the UK, and the University of Eastern Finland.

Over a 9-year follow-up period from mid-adolescence to young adulthood, insulin resistance decreased during growth from ages 15 through 17 years but increased from ages 17 through 24 years.