We are a multidisciplinary and translational research community, covering basic and applied research, epidemiology and clinical research, and providing a translation from laboratory to clinics. We believe that innovative methods enable new and cost-effective treatment paths in primary and secondary health care. We are globally the leading community in musculoskeletal research focusing both on osteoarthritis and osteoporosis. Our research community involves physicists, engineers, clinicians, biologists, and physiologists, supplemented with health economists, epidemiologists, and experts in quality of life research. This is a unique combination of disciplines in musculoskeletal research and there are no similar groups or consortia in the world. We are a world leader in musculoskeletal imaging, computational modeling, orthopedics, and epidemiology and we have developed, for example, novel imaging methods for diagnostics and modeling methods for the prediction of the disease progression.