Phenotyping Center


Phenotyping Center is part of Biocenter Finland Model Organisms platform (Mammalian model organisms). It is located at A.I. Virtanen Institute for Molecular Sciences and consists of Neurophenotyping and Cardiovascular Phenotyping units.

The Neurophenotyping Unit provides a large scale of behavioral assays, in vivo electrophysiological recordings in both freely moving and anesthetized animals, demanding tissue sampling, stereotactic brain injections, and brain histopathological analysis in mice and rats.  In addition, in collaboration with Neuroscience Center Mouse Behavioural Phenotyping Facility (MBPF), it accounts for academic training in neurophenotyping in Finland. The neurophenotyping unit runs and coordinates studies to characterize the neurophenotype of genetically modified rodent disease models or pre-clinical in vivo studies to assess the effect of novel treatments for CNS disorders.
    
The Cardiovascular Phenotyping Unit provides state-of-the-art analyses of cardiovascular structure and function especially with mice, but also with rats, rabbits and pigs. This includes both cardiovascular ultrasound imaging and histological analysis.

Because of nationally unique in vivo imaging infrastructure the ultrasound analysis can be further completed with cardiovascular MRI imaging. See more on Kuopio Biomedical Imaging Unit (Kuopio-BIU) pages.