Alzheimer Research

Data-analysis and bioinformatics of Alzheimer's disease

Anette Hall
D.Sc. (Tech.), Post-doctoral Researcher

University of Eastern Finland
Institute of Clinical Medicine / Neurology
P.O.Box 1627 (Yliopistonranta 1C)
FI-70211 Kuopio
Finland

+358-(0)40-3552385
anette.hall (at) uef.fi
room: Ca-5044

Academic Degrees

  • D.Sc. (Tech.) in Technical Physics (Computational Biophysics), Tampere University of Technology, 2011
  • M.Sc. (Tech.) in Technical Physics (Computational Biophysics), Tampere University of Technology, 2007

Major Positions and Appointments

  • Post-Doctoral Researcher, Department of Neurology, University of Eastern Finland, 2011-
  • Researcher, Ph.D. Student, Department of Physics (Biological Physics), Tampere University of Technology, Finland, 2007-2011
  • Research Assistant, M.Sc. Student, Department of Physics (Biological Physics), Tampere University of Technology, Finland, 2006-2007
  • Research Assistant, Department of Physics  (Applied Optics), Tampere University of Technology, Finland, 2004
  • Teaching Assistant, Department of Physics, Tampere University of Technology, Finland, 2007-2010

Selected Publications

Predicting Progression from Cognitive Impairment to Alzheimer's Disease with the Disease State Index. Hall A, Mattila J, Koikkalainen J, Lötjonen J, Wolz R, Scheltens P, Frisoni G, Tsolaki M, Nobili F, Freund-Levi Y, Minthon L, Frölich L, Hampel H, Visser PJ and Soininen H. Current Alzheimer Research. Accepted.

The effect of TOMM40 poly-T repeat lengths on age of onset and CSF biomarkers in Finnish Alzheimer's disease patients. Helisalmi S, Hall A, Meriläinen E-H, Väisänen V, Koivisto A M, Herukka S-K, Laitinen M, Soininen H and Hiltunen M. Neurodegener Dis 2014;14:204-208.

Generalizability of the Disease State Index Prediction Model for Identifying Patients Progressing from Mild Cognitive Impairment to Alzheimer's Disease. Hall A, Muñoz-Ruiz M, Mattila J, Koikkalainen J, Tsolaki M, Mecocci P, Kloszewska I, Vellas B, Lovestone S, Visser PJ, Lötjonen J, Soininen H. J Alzheimers Dis. 2014 Sep 8.

Effects of Alzheimer's disease-associated risk Loci on cerebrospinal fluid biomarkers and disease progression: a polygenic risk score approach. Martiskainen H, Helisalmi S, Viswanathan J, Kurki M, Hall A, Herukka SK, Sarajärvi T, Natunen T, Kurkinen KM, Huovinen J, Mäkinen P, Laitinen M, Koivisto AM, Mattila KM, Lehtimäki T, Remes AM, Leinonen V, Haapasalo A, Soininen H, Hiltunen M. J Alzheimers Dis. 2015 Jan 1;43(2):565-73.

Comparing predictors of conversion to Alzheimer's disease using the disease state index. Muñoz-Ruiz MÁ, Hall A, Mattila J, Koikkalainen J, Herukka SK, Vanninen R, Liu Y, Lötjönen J, Soininen H; Alzheimer's Disease Neuroimaging Initiative. Neurodegener Dis. 2014;13(2-3):200-2.

Genetic loci associated with Alzheimer's disease and cerebrospinal fluid biomarkers in a Finnish case-control cohort. Elias-Sonnenschein LS, Helisalmi S, Natunen T, Hall A, Paajanen T, Herukka SK, Laitinen M, Remes AM, Koivisto AM, Mattila KM, Lehtimäki T, Verhey FR, Visser PJ, Soininen H, Hiltunen M. PLoS One. 2013;8(4):e59676.

Disease state fingerprint in frontotemporal degeneration with reference to Alzheimer's disease and mild cognitive impairment. Muñoz-Ruiz MÁ, Hartikainen P, Hall A, Mattila J, Koikkalainen J, Herukka SK, Julkunen V, Vanninen R, Liu Y, Lötjönen J, Soininen H. J Alzheimers Dis. 2013;35(4):727-39.

Effect of galactosylceramide on the dynamics of cholesterol-rich lipid membranes. Hall A, Róg T, Vattulainen I.  J Phys Chem B. 2011 Dec 15;115(49):14424-34.

Role of lipids in spheroidal high density lipoproteins. Vuorela T, Catte A, Niemelä PS, Hall A, Hyvönen MT, Marrink SJ, Karttunen M, Vattulainen I.  PLoS Comput Biol. 2010 Oct 28;6(10).

Role of glycolipids in lipid rafts: a view through atomistic molecular dynamics simulations with galactosylceramide. Hall A, Róg T, Karttunen M, Vattulainen I. J Phys Chem B. 2010 Jun 17;114(23):7797-807.

Modeling of the triglyceride-rich core inlipoprotein particles. Hall A, Repakova J, Vattulainen I. J Phys Chem B. 2008 Nov 6;112(44):13772-82.