Molecular and Functional Genetics
 

"To establish the entire cascade starting from identification of risk genes involved in Alzheimer's disease by means of genetics followed by functional approaches to comprehensively assess the role of candidate genes and pathways relevant for molecular AD pathogenesis, such as in APP processing."

Methodology used includes techniques used conventionally in molecular and cellular biology (overexpression/RNAi of proteins, Western blotting etc.) as well as in molecular genetics (SNPing, quantitative PCR, sequencing etc.). 

Major Research Interests

• Identification of novel risk genes in Alzheimer's disease by means of molecular genetics
• Functional characterization of candidate genes involved in Alzheimer's disease in vitro and in vivo
• Molecular genetics of other neurodegenerative diseases