Biomaterials - Selected publications

Selected publications that are carried out in co-operation with Biomaterials laboratory at SIB Labs, Kuopio Campus for years 2012, 2013, 2014 and 2015 are listed below:

Year 2015

  • Rilla K, Koistinen AP. Correlative light and electron microscopy (CLEM) reveals the HAS3-induced dorsal plasma membrane ruffles. International Journal of Cell Biology (Accepted)
  • Kullaa A, Singh SP, Mikkonen JJP, Koistinen A. Optical spectroscopy in therapy response monitoring: An awakening giant. Spectroscopy Europe 2015: 27, 6-10.
  • Ukkonen H, Kumar S, Mikkonen J, Salo T, Singh SP, Koistinen A, Goormaghtigh E, Kullaa A. Changes in the microenvironment of invading melanoma and carcinoma cells identified by FTIR imaging. Vibrational Spectroscopy 2015: 79, 24-30.
  • Asikainen P, Sirviö E, Mikkonen J, Singh SP, Schulten EAJM, ten Bruggenkate CM, Koistinen AP, Kullaa AM. Microplicae – specialized cell interface between oral epithelium and saliva. Ultrastructural pathology. Early Online, 1-7, 2015.
  • Juvonen T, Nuutinen JP, Koistinen AP, Kröger H, Lappalainen R. Biomechanical evaluation of bone screw fixation with a novel bone cement. BioMedical Engineering Online 2015, 14:74

Selected publications from our customers

  • Tong XY, Malo M, Tamminen IS, Isaksson H, Jurvelin JS and Kroger H. Development of new criteria for cortical bone histomorphometry in femoral neck: intra- and inter-observer reproducibility. J Bone Miner Metab. 2015 Jan;33(1):109-18.
  • Näkki S, Rytkönen J, Nissinen T, Florea C, Riikonen J, Ek P, Zhang H, Santos HA, Närvänen A, Xu W, Lehto VP. Improved stability and biocompatibility of nanostructured silicon drug carrier for intravenous administration. Acta Biomater. 2015 Feb;13:207-15
  • Uski O, Jalava PI, Happo MS, Torvela T, Leskinen J, Mäki-Paakkanen J, Tissari J, Sippula O, Lamberg H, Jokiniemi J, Hirvonen MR. Effect of fuel zinc content on toxicological responses of particulate matter from pellet combustion in vitro. Sci Total Environ. 2015 Apr 1;511:331-40. doi: 10.1016/j.scitotenv.2014.12.061. Epub 2014 Dec 29.
  • Riikonen J, Correia A, Kovalainen M, Näkki S, Lehtonen M, Leppänen J, Rantanen J, Xu W, Araújo F, Hirvonen J, Järvinen K, Santos HA, Lehto VP. Systematic in vitro and in vivo study on porous silicon to improve the oral bioavailability of celecoxib. Biomaterials. 2015 Jun;52:44-55.
  • Xu W, Thapa R, Liu D, Nissinen T, Granroth S, Närvänen A, Suvanto M, Santos HA, Lehto VP. Smart Porous Silicon Nanoparticles with Polymeric Coatings for Sequential Combination Therapy. Mol Pharm. 2015 Nov 2;12(11):4038-47.
  • Kaarniranta K, Szalai E, Smedowski A, Hegyi Z, Kivinen N, Viiri J, Wowra B, Dobrowolski D, Módis L Jr, Berta A, Wylegala E, Felszeghy S. A novel proteotoxic stress associated mechanism for macular corneal dystrophy. Histol Histopathol. 2015 Aug;30(8):921-30
  • Oeder S, Kanashova T, Sippula O, et al. Particulate matter from both heavy fuel oil and diesel fuel shipping emissions show strong biological effects on human lung cells at realistic and comparable in vitro exposure conditions. PLoS One. 2015 Jun 3;10(6):e0126536

Year 2014

  • Kawaji H, Koistinen A, Korhonen RK, Lappalainen R, Lohman M, Soininen A, Gomez-Barrena E, Konttinen YT, Ylinen P, Talloroth K. Back-side wear in HexLoc cups clinico-radiological, immunohistopathological, finite element and retrieval analysis studies. J Long-Term Effects of Medical Implants 2014: 24, 319-331.
  • Vaario L-M, Lu J, Koistinen A, Tervahauta A, Aronen T. Variation among matsutake ectomycorrhizae in four clones of Pinus sylvestris. Mycorrhiza (Accepted). DOI 10.1007/s00572-014-0601-8
  • Koistinen AP, Korhonen H, Kröger H, Lappalainen R. Interfacial sliding properties of bone screw materials and their effect on screw fixation strength. Journal of Applied Biomaterials & Functional Materials 2014: 12 (2), 90-96. DOI: 10.5301/jabfm.5000177
  • Kinnunen K, Kauppinen AA, Laakso N, Koistinen A, Toropainen E, Kaarniranta K. Cationorm shows good tolerability on human HCE-2 corneal epithelial cell cultures. Experimental Eye Research 2014: 120C, 82-89.
  • Koistinen AP, Isaksson H, Arokoski JPA, Brama PA, Jurvelin JS, Helminen HJ. Short-term exercise-induced improvements in bone properties were are for the most part not maintained during ageing in hamsters. Experimental Gerontology 2014: 51, 46-53.
  • Asikainen P, Mikkonen JJ, Ruotsalainen TJ, Koistinen AP, Kullaa AM. Microstructure of the superficial epithelial cells of oral mucosa. Ultrastructural pathology 2014: 38, 6-12.

Selected publications from our customers

  • Qu C, Rilla K, Tammi R, Tammi M, Kröger H, Lammi MJ. Extensive CD44-dependent hyaluronan coats on human bone marrow-derived mesenchymal stem cells produced by hyaluronan synthases HAS1, HAS2 and HAS3. Int J Biochem Cell Biol. 2014 Mar;48:45-54.
  • Törrönen K, Nikunen K, Kärnä R, Tammi M, Tammi R, Rilla K. Tissue distribution and subcellular localization of hyaluronan synthase isoenzymes. Histochem Cell Biol. 2014 Jan;141(1):17-31.
  • Rilla K, Siiskonen H, Tammi M, Tammi R. Hyaluronan-coated extracellular vesicles--a novel link between hyaluronan and cancer. Adv Cancer Res. 2014;123:121-48.
  • Turunen MJ, Lages S, Labrador A, Olsson U, Tagil M, Jurvelin JS and Isaksson H. Evaluation of composition and mineral structure of callus tissue in rat femoral fracture. J Biomed Opt. 2014 Feb;19(2):025003
  • Rieppo L, Saarakkala S, Jurvelin JS and Rieppo J. Optimal variable selection for Fourier transform infrared spectroscopic analysis of articular cartilage composition. J Biomed Opt. 2014 Feb;19(2):027003
  • Vlasova MA, Rytkönen J, Riikonen J, Tarasova OS, Mönkäre J, Kovalainen M, Närvänen A, Salonen J, Herzig KH, Lehto VP, Järvinen K. Nanocarriers and the delivered drug: effect interference due to intravenous administration. Eur J Pharm Sci. 2014 Oct 15;63:96-102
  • Rytkönen J, Arukuusk P, Xu W, Kurrikoff K, Langel U, Lehto VP, Närvänen A. Porous silicon-cell penetrating peptide hybrid nanocarrier for intracellular delivery of oligonucleotides. Mol Pharm. 2014 Feb 3;11(2):382-90
  • Turunen E, Korhonen O, Lehto VP, Kauppinen A, Ahtiainen H, Järvinen K, Jarho P. Effect of storage on the dissolution rate of a fast-dissolving perphenazine/β-cyclodextrin complex. J Pharm Pharmacol. 2014 Mar;66(3):367-77.
  • Kivimäenpää M, Riikonen J, Sutinen S, Holopainen T. Cell structural changes in the mesophyll of Norway spruce needles by elevated ozone and elevated temperature in open-field exposure during cold acclimation. Tree Physiol. 2014 Apr;34(4):389-403.
  • T. Torvela, J. Tissari, O. Sippula, T. Kaivosoja, J. Leskinen, A. Virén, A. Lähde, J. Jokiniemi. Effect of wood combustion conditions on the morphology of freshly emitted fine particles. Atmospheric Environment, Volume 87, April 2014, Pages 65-76
  • J. Leskinen, J. Tissari, O. Uski, A. Virén, T. Torvela, T. Kaivosoja, H. Lamberg, I. Nuutinen, T. Kettunen, J. Joutsensaari, P.I. Jalava, O. Sippula, M.-R. Hirvonen, J. Jokiniemi. Fine particle emissions in three different combustion conditions of a wood chip-fired appliance –Particulate physico-chemical properties and induced cell death. Atmospheric Environment, Volume 86, April 2014, Pages 129-139
  • M. Ihalainen, T. Lind, J. Ruusunen, P. Tiitta, A. Lähde, T. Torvela, J. Jokiniemi. Experimental study on bounce of submicron agglomerates upon inertial impaction. Powder Technology, Volume 268, December 2014, Pages 203-209
  • Leskinen J, Ihalainen M, Torvela T, Kortelainen M, Lamberg H, Tiitta P, Jakobi G, Grigonyte J, Joutsensaari J, Sippula O, Tissari J, Virtanen A, Zimmermann R, Jokiniemi J. Effective density and morphology of particles emitted from small-scale combustion of various wood fuels. Environ Sci Technol. 2014 Nov 18;48(22):13298-306.
  • Torvela T, Uski O, Karhunen T, Lähde A, Jalava P, Sippula O, Tissari J, Hirvonen MR, Jokiniemi J. Reference particles for toxicological studies of wood combustion: formation, characteristics, and toxicity compared to those of real wood combustion particulate mass. Chem Res Toxicol. 2014 Sep 15;27(9):1516-27.

Year 2013

  • Pöllänen M, Suihkonen R, Nevalainen K, Koistinen AP, Suvanto M, Vuorinen J, Pakkanen TT. Morphological, Mechanical, Tribological, and Thermal Expansion Properties of Organoclay Reinforced Polyethylene Composites. Polymer Engineering and Science.2013: 53, 1279-1286.
  • Qu C, Myllymaa S, Prittinen J, Koistinen A, Lappalainen R, Lammi MJ. Osteoblast behavior on various ultra short pulsed laser deposited surface coatings. Journal of Materials Science and Engineering C 2013: 33, 1676-1682.

Selected publications from our customers

  • Kaitainen S, Mähönen AJ, Lappalainen R, Kröger H, Lammi MJ, Qu C. TiO2 coating promotes mesenchymal stem cell proliferation without the loss of their capacity for chondrogenic differentiation. Biofabrication. 2013.
  • Myllymaa K, Levon J, Tiainen VM, Myllymaa S, Soininen A, Korhonen H, Kaivosoja E, Lappalainen R, Konttinen YT. Formation and retention of staphylococcal biofilms on DLC and its hybrids compared to metals used as biomaterials. Colloids and Surfaces B: Biointerfaces, Volume 101, 1 January 2013, Pages 290-297
  • Kaivosoja E, Myllymaa S, Takakubo Y, Korhonen H, Myllymaa K, Konttinen YT, Lappalainen R, Takagi M. Osteogenesis of human mesenchymal stem cells on micro-patterned surfaces. J Biomater Appl. 2013 Mar;27(7):862-71.
  • Rieppo L, Narhi T, Helminen HJ, Jurvelin JS, Saarakkala S and Rieppo J. Infrared spectroscopic analysis of human and bovine articular cartilage proteoglycans using carbohydrate peak or its second derivative. J Biomed Opt. 2013 Sep;18(9):097006. doi: 10.1117/1.JBO.18.9.097006.
  • Rautiainen J, Lehto LJ, Tiitu V, Kiekara O, Pulkkinen H, Brunott A, van Weeren R, Brommer H, Brama PA, Ellermann J, Kiviranta I, Nieminen MT and Nissi MJ. Osteochondral repair: evaluation with sweep imaging with fourier transform in an equine model. Radiology. 2013 Oct;269(1):113-21. doi: 10.1148/radiol.13121433. Epub 2013 May 14.
  • Kulmala KA, Karjalainen HM, Kokkonen HT, Tiitu V, Kovanen V, Lammi MJ, Jurvelin JS, Korhonen RK and Toyras J. Diffusion of ionic and non-ionic contrast agents in articular cartilage with increased cross-linking--contribution of steric and electrostatic effects. Med Eng Phys. 2013 Oct;35(10):1415-20. doi: 10.1016/j.medengphy.2013.03.010. Epub 2013 Apr 24.
  • Tamminen IS, Yli-Kyyny T, Isaksson H, Turunen MJ, Tong X, Jurvelin JS and Kroger H. Incidence and bone biopsy findings of atypical femoral fractures. J Bone Miner Metab. 2013 Sep;31(5):585-94. doi: 10.1007/s00774-013-0448-7. Epub 2013 Apr 4.
  • Rieppo L, Saarakkala S, Jurvelin JS and Rieppo J. Prediction of compressive stiffness of articular cartilage using Fourier transform infrared spectroscopy. J Biomech. 2013 Apr 26;46(7):1269-75. doi: 10.1016/j.jbiomech.2013.02.022. Epub 2013 Mar 26.
  • Turunen MJ, Prantner V, Jurvelin JS, Kroger H and Isaksson H. Composition and microarchitecture of human trabecular bone change with age and differ between anatomical locations. Bone. 2013 May;54(1):118-25. doi: 10.1016/j.bone.2013.01.045. Epub 2013 Feb 4.
  • Rilla K, Pasonen-Seppänen S, Deen AJ, Koistinen VV, Wojciechowski S, Oikari S, Kärnä R, Bart G, Törrönen K, Tammi RH, Tammi MI. Hyaluronan production enhances shedding of plasma membrane-derived microvesicles. Exp Cell Res. 2013 Aug 1;319(13):2006-18.
  • Viiri J, Amadio M, Marchesi N, Hyttinen JM, Kivinen N, Sironen R, Rilla K, Akhtar S, Provenzani A, D'Agostino VG, Govoni S, Pascale A, Agostini H, Petrovski G, Salminen A, Kaarniranta K. Autophagy activation clears ELAVL1/HuR-mediated accumulation of SQSTM1/p62 during proteasomal inhibition in human retinal pigment epithelial cells. PLoS One. 2013 Jul 29;8(7):e69563.
  • Klettner A, Kauppinen A, Blasiak J, Roider J, Salminen A, Kaarniranta K.Cellular and molecular mechanisms of age-related macular degeneration: from impaired autophagy to neovascularization. Int J Biochem Cell Biol. 2013 Jul;45(7):1457-67.

Year 2012

  • Lammi MJ, Qu C, Prittinen J, Kröger H, Koistinen A, Myllymaa S, Lappalainen R. Adhesion and spreading of different skeletal cell types on variable surface coatings. IEEE Xplore Trans Biomed Eng Infor 2012: 582-587
  • Juvonen T, Koistinen A, Kröger H, Lappalainen R. Enhanced bone screw fixation with biodegradable bone cement in osteoporotic bone model. Journal of Applied Biomaterials & Functional materials 2012; 10: e113-8.
  • Asikainen P, Ruotsalainen T, Mikkonen J, Koistinen A, ten Bruggenkate C, Kullaa A. The defense architecture of the superficial cells of the oral mucosa. Medical hypotheses 2012; 78:790-2.
  • Turunen SM, Lammi MJ, Saarakkala S, Koistinen A, Korhonen RK. Hypotonic Challenge Modulates Cell Volumes Differently in Intact Articular Cartilage and Cartilage Explant. Biomechanics and Modeling in Mechanobiology, 2012; 11: 665-675.