Working Group 1:
Cancer Genetics

  • Strength of genetic studies of an isolated population, high quality clinical data and material from Kuopio University Hospital area in the search for cancer risk factors and gene-environment -interactions
  • Role of EMT related proteins and genes and qualitative and quantitative genetic alterations in the microenvironment of epithelial malignancies
  • Genetics and personalized medicine in cancer treatment - pharmacogenetics
  • Continue to investigate genetic factors with BCAC
  • Role of cancer stem cells in stroma-epithelium microenvironment
New prospective
breast cancer project
risk variants


Figure: Effect of a matriptase-1 expression variant on breast cancer patient survival.